TCM Research:
ACMS Research Ethics Committee (REC)

Chinese version is currently not available

About Us

The Academy of Chinese Medicine, Singapore Research Ethics Committee (ACMS-REC) is established under ACMS Council. This Board is an independent Traditional Chinese Medicine (TCM) ethics review committee which reviews, approves and monitors the ethical aspects of TCM research projects upon human subjects. The research may be conducted at an affiliated ACMS research institution or other research institution(s) without an affiliated Ethics Committee/Institutional Review Board.

Our main objective is to protect the rights and welfare of potential research subjects and also promote high ethical standards in TCM research.


An overview of the initial application submission and review process is as follows:

ACMS-REC shall provide researcher(s) with an initial outcome of its review of the proposed research project 2 weeks after the REC board review.

For simple, straightforward Protocol Amendments (i.e. changes in Principal Investigator, Co-Investigator(s) and/or contact information), ACMS-REC need to be informed within 7 working days. Otherwise, it would follow the above timeline for the new application.

The PI is to submit written summaries of the progress of the research to ACMS-REC every quarterly.

All unexpected serious adverse events related to the research would need to be reported immediately to ACMS-REC.

Forms Submission

This section is strictly for submissions approved by the ACMS REC.

Principal Investigators seeking to extend their REC approval must submit a Study Status Report at least 2 months before the REC approval period ends.

Principal Investigators should use the document templates available for download below:

    1. Study Status Report Form (Study Closure, Renewal, Reactivation will use this form)
    2. ACMS REC Amendment Form
    3. ACMS REC Local Serious Adverse Effect (SAE) Reporting Form
    4. ACMS REC Protocol Deviation and Non-Compliance Form


Applications are accepted throughout the year. Principal Investigators (PI) are expected to follow the submission guidelines strictly in the REC Application form.

Softcopies of completed applications and requisite supporting documents of the following requirements should be submitted by email to

For ease of reference, please use the email subject heading “ACMS REC Application – [Simplified Study Title]’ (e.g. “ACMS REC Application – Effect of XX”) and addressed email to secretariat of ACMS REC.

ACMS REC Application FormWord AND PDF (signed and scanned in full colour)
  • Qualifications of PI and Co-I(s)
    • CITI and/or GCP certificates of PI and Co-I(s) (If applicable)
      Please ensure that the CITI certificates are still valid and not expired.
    • CVs of PI, Co-I(s) and Collaborator(s) (1-page each)
      Please ensure that the CV does not include sensitive information like identification number and home address.

Other Supporting Documents

If Applicable:

  • Study Protocol
  • Lay Summary of Research
  • Participant Information Sheet and Consent Form (Research Study and/or Video and Photography)*
  • Questionnaires/Survey Forms/Interview Guides (If applicable)*
  • Recruitment Materials* (e.g) Invitation Letters/ Emails/Phone Scripts * Advertisements (If applicable)
  • Payment to subjects and Payment Schedule
  • List of variables to be extracted from medical records database (If applicable)
  • Copy of grant award letter (For funded studies)

*Please submit these documents in additional languages, e.g. Mandarin, Malay and Tamil (if applicable). Do note that PIs are responsible for the accuracy of the translations.


The original signed hard copy of application form and supporting documents (CVs of PI, Co-I and Collaborators) should be mailed to:

Secretariat of ACMS-REC
Academy of Chinese Medicine, Singapore
705 Serangoon Road
Singapore 328127

For changes in the protocol, ACMS-REC should be informed within 7 working days.

Will be updated soon

Fees & Payment

Types of ReviewACMS*Non-ACMS
Initial ApplicationClinical Trial which includes intervention of TCM herbs/ acupuncture/ manipulation
[*Currently Not Available for Review]
Medical Records Review50100
Subsequent Amendments2550
Subsequent Site Amendments50100

*This is applicable to studies at host institution related to Individual ACMS members or initiated by industry or commercial entities. ACMS initiated research projects would not need a review fee.

Payment must be made payable to Academy of Chinese Medicine, Singapore by Cheque or Bank Transfer.

The cheque with cover sheet: Must be submitted and mail to us at

Secretariat of ACMS-REC
Academy of Chinese Medicine, Singapore
705 Serangoon Road, Singapore 328127

For Bank Transfer with cover sheet: To provide proof of payment slip/screen shot of payment and email us at

Download Cover sheet

Contact Us

For queries, you may refer to the Frequently Answered Questions (will be updated soon) or contact the ACMS REC Executive at